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How much air is needed to kill you? That’s debatable and doubtless varies, but generally speaking, a lot. One journal article I saw boldly declared that 300 milliliters can be lethal — three-tenths of a liter! You’d need a bicycle pump to inject that. But much less will do the trick; it’s said serious damage can result from as little as 20 milliliters, which still isn’t a small amount. In 1949 New Hampshire physician Hermann Sander ended the life of a terminal cancer patient by injecting her with 40 milliliters of air — four syringes of 10 milliliters each.
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